"Evidence suggests collagen peptides improve skin hydration and elasticity, which may provide a means to improve skin health as we age."

Dr. Brad Stanfield, a physician focusing on longevity

The Longevity Benefits of Collagen Peptides

Collagen peptides, especially bioactive forms like VERISOL® collagen peptides, have gained significant attention for their role in promoting skin health, joint integrity, and overall longevity. As the most abundant protein in the human body, collagen plays a critical role in maintaining the structural integrity of tissues, including skin, bones, and joints. However, as we age, natural collagen production declines, leading to visible signs of aging and decreased functionality in connective tissues. Supplementation with collagen peptides has emerged as a science-backed intervention to address these age-related changes.

What Are Collagen Peptides?

Collagen peptides are short chains of amino acids derived from hydrolyzed collagen. This form of collagen is highly bioavailable, meaning it is easily absorbed and utilized by the body. Once ingested, collagen peptides travel through the bloodstream to areas where repair and regeneration are needed, such as the skin, joints, and bones. They serve as building blocks and signaling molecules, stimulating the production of new collagen and other extracellular matrix components essential for tissue health.

Primary Longevity Benefits of Collagen Peptides

1. Enhancing Skin Elasticity and Reducing Wrinkles

One of the most well-documented benefits of collagen peptides is their ability to improve skin health. Studies have shown that bioactive collagen peptides can significantly increase skin elasticity, hydration, and dermal density while reducing the depth of wrinkles.

Clinical Evidence:

  • A study published in Skin Pharmacology and Physiology (2014) demonstrated that women who took 2.5 grams of VERISOL® collagen peptides daily for 8 weeks experienced a 20% reduction in wrinkle depth around the eyes, with effects sustained even four weeks after stopping supplementation.
  • Another study involving 69 women aged 35-55 found that 8 weeks of VERISOL® supplementation significantly improved skin elasticity compared to a placebo, with the most pronounced benefits observed in older participants.

Mechanism: Collagen peptides stimulate dermal fibroblasts to produce more collagen and elastin, the proteins responsible for maintaining skin’s firmness and elasticity. Additionally, they inhibit matrix metalloproteinases (MMPs), enzymes that degrade collagen in the skin.

2. Supporting Joint Health and Mobility

Collagen is a vital component of cartilage, the tissue that cushions joints. As we age, cartilage becomes thinner and less resilient, often leading to joint discomfort and reduced mobility. Collagen peptides have been shown to support joint health by promoting cartilage repair and reducing inflammation.

Clinical Evidence:

  • Research in Current Medical Research and Opinion (2006) found that daily supplementation with collagen hydrolysate significantly reduced joint pain in patients with osteoarthritis over six months.
  • Athletes with activity-related joint pain reported improved joint function and reduced discomfort after 24 weeks of collagen peptide supplementation.

Mechanism: Collagen peptides stimulate chondrocytes (cartilage cells) to produce type II collagen and proteoglycans, essential components of healthy cartilage. They also reduce inflammation in joint tissues, alleviating pain and stiffness.

3. Improving Bone Density

Age-related bone loss, or osteoporosis, is a major concern for longevity. Collagen peptides play a crucial role in bone health by enhancing bone mineral density and promoting the synthesis of bone matrix proteins.

Clinical Evidence: A randomized controlled trial published in Nutrients (2018) found that postmenopausal women who supplemented with 5 grams of specific collagen peptides daily for 12 months experienced significant increases in bone mineral density and reductions in bone turnover markers.

Mechanism: Collagen peptides provide the amino acids necessary for the synthesis of type I collagen, the primary organic component of bone. This strengthens the bone matrix and reduces the risk of fractures.

4. Promoting Cellular Repair and Reducing Oxidative Stress

Collagen peptides contain high levels of glycine, proline, and hydroxyproline—amino acids that support cellular repair and reduce oxidative stress, both critical factors in slowing the aging process.

Mechanism: Glycine acts as an anti-inflammatory agent, while proline and hydroxyproline stimulate antioxidant pathways. Together, these amino acids help neutralize free radicals and protect tissues from oxidative damage.

Additional Functional Benefits

1. Improved Nail and Hair Health

VERISOL® collagen peptides have shown remarkable benefits for nails and hair, making them an essential component of beauty-from-within regimens.

Clinical Evidence:

  • A study published in Journal of Cosmetic Dermatology (2017) revealed that daily intake of VERISOL® collagen peptides for 24 weeks reduced cracked and chipped nails by 42% and significantly increased nail growth.
  • In vitro studies showed a 31% increase in hair follicle cell proliferation rates with VERISOL® supplementation.

2. Supporting Gut Health

Collagen peptides contribute to the integrity of the gut lining, reducing intestinal permeability and promoting healthier digestion.

Mechanism: By supplying amino acids essential for mucosal repair, collagen peptides strengthen the gut barrier, reducing inflammation and improving nutrient absorption.

3. Accelerating Recovery and Muscle Repair

For those who engage in physical activity, collagen peptides support muscle recovery and connective tissue repair, enabling sustained performance and mobility.

Clinical Evidence: Athletes who supplemented with collagen peptides reported faster recovery times and reduced muscle soreness.

VERISOL® Collagen Peptides: A Gold Standard in Longevity

VERISOL® collagen peptides stand out due to their high bioactivity and clinically proven benefits. Unlike generic collagen supplements, VERISOL® has been specifically formulated to target skin, nail, and hair health with precision.

Key Benefits of VERISOL®:

Reduces eye wrinkle volume by 20% within 8 weeks.

Improves skin elasticity and hydration, particularly in older adults.

Enhances nail growth and strength, reducing brittleness by 42%.

Stimulates hair follicle cell proliferation by 31%, promoting thicker, healthier hair.

How to Incorporate Collagen Peptides for Longevity

To maximize the benefits of collagen peptides, consider the following guidelines:

  • Dosage: Most studies recommend 2.5 to 10 grams daily for optimal results, depending on the form of collagen peptide. VERISOL® requires a 2.5g daily dose. 
  • Timing: Collagen peptides can be taken at any time, but combining them with vitamin C may enhance collagen synthesis.
  • Consistency: Long-term supplementation is key to maintaining benefits, as collagen production naturally declines with age.

Conclusion

Collagen peptides, particularly bioactive forms like VERISOL®, offer a scientifically supported approach to enhancing longevity and overall health. From reducing wrinkles and improving skin elasticity to supporting joint, bone, and gut health, collagen peptides provide a holistic solution to the challenges of aging. Backed by robust clinical evidence, these peptides empower individuals to take control of their aging process and promote a healthier, more vibrant future.

How Collagen Peptides Impacts Aging:

Specific Hallmarks:

  • Loss of Proteostasis: Collagen peptides provide essential amino acids that support protein turnover and repair, helping to maintain the balance of cellular proteins and reduce aggregation linked to aging.
  • Cellular Senescence: By improving the extracellular matrix and reducing inflammation, collagen peptides may help mitigate senescent cell accumulation in tissues, supporting healthier cellular environments.
  • Deregulated Nutrient Sensing: Collagen peptides influence metabolic pathways like mTOR by providing glycine and proline, which support balanced nutrient sensing and promote tissue repair.
  • Stem Cell Exhaustion: Collagen supplementation supports the structural environment of stem cell niches, which may aid in the maintenance and function of regenerative cells.

Mechanism of Action:

  • Enhanced Skin Hydration: Collagen peptides increase skin moisture levels, improving overall hydration and reducing dryness associated with aging.
  • Improved Joint Mobility: Regular supplementation supports cartilage repair and reduces joint stiffness, promoting better movement and quality of life.
  • Strengthened Nails and Hair: Clinical studies show collagen peptides enhance nail growth and reduce brittleness while stimulating hair follicle proliferation for thicker, healthier hair.
  • Gut Health Support: Collagen peptides reinforce the gut lining, improving nutrient absorption and reducing inflammation linked to gut permeability.
  • Accelerated Muscle Recovery: The amino acids in collagen peptides aid muscle repair and recovery post-exercise, preserving lean body mass during aging.

Scientific studies

  • VERISOL® Enhances Skin Elasticity and Reduces Wrinkles

    A double-blind, placebo-controlled study assessed the effectiveness of VERISOL® on eye wrinkle formation and skin elasticity. A total of 114 women aged 45-65 received 2.5 grams of VERISOL® or a placebo daily for 8 weeks. Results showed a significant reduction in eye wrinkle volume after 4 and 8 weeks of supplementation, with a 20% decrease observed. Additionally, skin elasticity improved compared to the placebo group. The study concluded that VERISOL® stimulates collagen metabolism, leading to noticeable improvements in skin appearance. Reference: Skin Pharmacology and Physiology, 2014. "Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis." Research conducted by Proksch et al.

  • VERISOL® Improves Nail Growth and Reduces Brittleness

    A study evaluated the effect of VERISOL® on nail health in participants with brittle nail syndrome. Participants received a daily dose of VERISOL® for 6 months. The results demonstrated a 42% decrease in cracked and/or chipped nails after 6 months of treatment. Additionally, nail growth increased, and the frequency of broken nails decreased during the supplementation period. The study suggests that VERISOL® supplementation can improve nail growth and reduce brittleness. Reference: Study presented by GELITA. 2017. "Effects of Specific Collagen Peptides on Nail Growth and Structure." Research conducted in Germany.

  • VERISOL® Increases Hair Thickness

    A peer-reviewed study investigated the impact of VERISOL® on hair structure. Participants received a daily dose of VERISOL® for 16 weeks. The study observed an increase in hair thickness among participants, indicating that VERISOL® supplementation can positively affect hair structure. The researchers noted that the increased hair thickness likely leads to improved textural and physical properties of hair, making it stronger and more resistant to breakage. Reference: Research conducted by GELITA, 2017. "The Impact of VERISOL® on Hair Structure and Thickness."

  • VERISOL® Reduces Cellulite

    A clinical study examined the effect of VERISOL® on cellulite treatment. Participants received a daily dose of VERISOL® for 6 months. The study results showed a significant reduction in the degree of cellulite and a decrease in skin waviness on the thighs in women of normal body weight who took VERISOL® compared to the placebo group. Additionally, skin density improved in the VERISOL® group. The study suggests that regular intake of specific collagen peptides for 6 months can lead to a noticeable improvement in the appearance of skin in women with moderate cellulite. Reference: Journal of Medicinal Food, 2015. "Specific Bioactive Collagen Peptides Reduce Cellulite." Research by Schunck et al.

Recommended Dosage

2.5g

per day

Source and origin

Collagen peptides, in their bioavailable form, are not naturally found in whole foods but are derived from natural sources through processing. For targeted benefits and consistent dosing, collagen peptide supplements are more practical and effective.

People Also Ask

  • Are collagen peptides safe for daily use?

    Yes, collagen peptides are generally safe for daily use in doses up to 10 grams, as supported by clinical studies. They are well-tolerated by most individuals, with minimal reported side effects.

  • Is there an optimal time of day to take collagen peptides?

    Collagen peptides can be taken at any time of day. For improved absorption, many experts recommend consuming them with a source of vitamin C, which enhances collagen synthesis.

  • Can collagen peptides be taken with other supplements?

    Yes, collagen peptides pair well with other supplements, such as vitamin C for enhanced synthesis or hyaluronic acid for synergistic skin benefits. Ensure the combined supplements align with your health goals and dosages.

  •  How long does it take to see results from collagen peptide supplementation?

    Results vary depending on the individual and the health goal. Clinical studies suggest improvements in skin elasticity and hydration may be noticeable within 4 to 8 weeks, while benefits for joints or nails may take 3 to 6 months.

  • Are collagen peptides effective for older adults?

    Yes, collagen peptides are particularly effective for older adults as natural collagen production decreases with age. Supplementation can help counteract age-related collagen loss and support joint, bone, and skin health.

References

  • Reference link

    Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network. Journal of Cosmetic Dermatology, 14(4), 291-301.

  • Reference link

    Bello, A. E., & Oesser, S. (2006). Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders. Current Medical Research and Opinion, 22(11), 2221-2232.

  • Reference link

    Clark, K. L., Sebastianelli, W., Flechsenhar, K. R., Aukermann, D. F., Meza, F., Millard, R. L., Deitch, J. R., Sherbondy, P. S., & Albert, A. (2008). 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Current Medical Research and Opinion, 24(5), 1485-1496.

  • Reference link

    Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacology and Physiology, 27(3), 113-119.

  • Reference link

    Zague, V., de Freitas, V., da Costa Rosa, M., de Castro, G. A., Jaeger, R. G., & Macedo Fdo, C. (2011). Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity. Journal of Medicinal Food, 14(6), 618-624.

  • Reference link

    Schunck, M., Zague, V., Oesser, S., & Proksch, E. (2015). Dietary supplementation with specific collagen peptides has a body mass index-dependent beneficial effect on cellulite morphology. Journal of Medicinal Food, 18(12), 1340-1348.

  • Reference link

    König, D., Oesser, S., Scharla, S., Zdzieblik, D., & Gollhofer, A. (2018). Specific collagen peptides improve bone mineral density and bone markers in postmenopausal women\u2014a randomized controlled study. Nutrients, 10(1), 97.

  • Reference link

    Hexsel, D., Zague, V., Schunck, M., Siega, C., & Camozzato, F. O. (2017). Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. Journal of Cosmetic Dermatology, 16(1), 72-77.

  • Kim, D. U., Chung, H. C., Choi, J., Sakai, Y., & Lee, B. Y. (2018). Oral intake of low-molecular-weight collagen peptide improves hydration, elasticity, and wrinkling in human skin: a randomized, double-blind, placebo-controlled study. Nutrients, 10(7), 826.

  • Reference link

    Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., Bagchi, D., Dey, D. K., & Raychaudhuri, S. P. (2009). Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. International Journal of Medical Sciences, 6(6), 312–321.

  • Zhu, C. F., Li, G. Z., Peng, H. B., Li, Y., Zhang, F., & Chen, Y. (2010). Therapeutic effects of marine collagen peptides on Chinese patients with type 2 diabetes mellitus and primary hypertension. The American Journal of the Medical Sciences, 340(5), 360-366. Ryazanov, A. G., & Nefsky, B. S. (2002). Protein turnover plays a key role in aging. Mechanisms of Ageing and Development, 123(2-3), 207-213.

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