Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
Glucose Blocker 2024
METABOLISM & SUGAR CONTROL

Glucose Blocker 2024

4.9/5
| 1155+ Verified Reviews
per month

Our Glucose Blocker, taken with meals, helps combat one of the leading lifestyle contributors to premature aging - volatile blood glucose levels. Modern diets are saturated with glucose, present in everything from processed carbohydrates to sugary desserts. Constant high blood glucose levels can result in insulin resistance and stimulate glycation, leading to inflammation, oxidative stress, and tissue harm - significant factors in skin aging. Glucose Blocker regulates post-meal glucose levels, providing steady energy without severe spikes and crashes associated with carb intake. Its natural ingredients decelerate glycation, prevent oxidative stress, and possess anti-inflammatory properties. Our proprietary formula features Berberine, an extraordinary molecule recognized for its ability to activate critical pathways linked to longevity. Plus, Glucose Blocker helps curtail the absorption of sugar-related calories, aiding in weight management and sugar reliance. Enjoy your carby meals with less guilt!

  • Subscribe & Save

    Save & get free metal storage canisters

  • 90-Day Guarantee

    Buy risk-free

  • Cancel anytime

    Cancel whenever you need
Glucose Blocker 2024
Ingredients
Chromium (as chromium chloride)
200 mcg
White Mulberry Leaf Extract
200 mg
Berberine HCL
200 mg
Gymnema Sylvestre Leaf Extract
180 mg
White Kidney Bean Extract
400 mg

As seen in

Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image
Marquee image

Cheat your cheat meals

Master your sugar, unlock your healthy longevity

Discover the unique benefits that set us apart.

Defy Blood Sugar Spikes

Enjoy carbs without the crash, guilt, or fatigue

Every carb-heavy meal triggers glucose spikes—leading to energy crashes, fatigue, belly fat, brain fog, and accelerated aging (33). Glucose Blocker smooths out these spikes, keeping your energy steady, mind clear, and metabolism optimized. Chromium boosts insulin sensitivity for improved glucose control (1), while berberine activates AMPK, your body's natural metabolism regulator, stabilizing blood sugar and enhancing insulin effectiveness (1,34). Gymnema sylvestre further maintains healthy glucose levels by moderating sugar absorption and liver glucose release (1). White mulberry leaf and white kidney bean extracts reduce carbohydrate breakdown, limiting the glucose entering your bloodstream (2). With Glucose Blocker, carbs fuel your day—without dragging your body or mind down.

All references

Combat Sugar-Induced Aging and Wrinkles

Fight wrinkles, rejuvenate skin, and activate your longevity genes.

Sugar doesn't just affect your waistline—it also accelerates aging by forming harmful molecules called AGEs, causing wrinkles, sagging skin, and age spots (3). Glucose Blocker tackles aging at the cellular level, reducing glycation and oxidative stress that prematurely age your skin. Berberine and mulberry leaf extract reduce inflammation and protect against AGE formation, preserving a youthful appearance (4).

But it doesn't stop there: Glucose Blocker also activates cutting-edge longevity pathways by stimulating the AMPK and FOXO3A proteins—your body's powerful anti-aging switches. Berberine and chromium chloride boost AMPK activation, enhancing metabolism and glucose management (26, 35, 36). Gymnema sylvestre and mulberry leaf extract further amplify AMPK and FOXO3A activity, enhancing cellular repair and antioxidant defenses for long-term cellular health (37, 38). The result? Healthier cells today, and stronger, younger skin for longer.

All references

Conquer Sugar Cravings

Kick your sweet tooth to the curb—for good.

Sugar cravings aren't just about hunger—they’re your brain’s way of asking for a quick reward (8). Glucose Blocker stops cravings in their tracks using Gymnema sylvestre, a plant known as the "sugar destroyer." Its gymnemic acid tricks your taste buds, reducing sugar's appeal and helping you resist sweet temptations (1, 9-15). Plus, white mulberry extract creates a natural feeling of fullness by slowing carb digestion, further calming cravings (16, 17). With Glucose Blocker, you'll finally break sugar’s hold, reclaiming control over what you eat and how you feel.

All references

Accelerate Metabolism & Weight Loss

Reduce calorie absorption, boost fat burning, and reignite metabolism.

Eating less isn't always enough to shed pounds—successful weight loss also requires smarter metabolism. Glucose Blocker delivers a powerful dual-action approach: it helps limit calorie absorption from carbs while naturally accelerating your metabolism to convert fat into energy. White mulberry leaf extract slows carbohydrate digestion, reducing calories absorbed from meals (17-21), and white kidney bean extract inhibits enzymes that turn carbs into sugars (17-21). Meanwhile, berberine activates AMPK—your body's natural metabolic "switch"—enhancing your fat-burning ability and helping you slim down faster (26, 35, 36). With Glucose Blocker, you'll experience visible progress on your weight-loss journey without the constant struggle.

All references

Smarter Cheat Meals

Reduce the impact of carbs and stay closer to your low-carb goals.

Sticking to a low carb or keto dier requires discipline—but occasional cheat meals happen. Glucose Blocker helps soften the impact of carb-rich indulgences by slowing carbohydrate digestion, keeping glucose spikes lower and more manageable (7,21,24). White mulberry leaf and white kidney bean extracts reduce how quickly carbs enter your bloodstream, minimizing disruptions to your metabolic state (7,24). Meanwhile, Gymnema sylvestre further slows glucose absorption, helping you rebound more easily after carb-heavy meals (25). With Glucose Blocker, you can enjoy occasional treats without completely derailing your progress.

All references

Combat Inflammation, Bolster Antioxidant Defense

For Whole Body Health

Pervasive inflammation can accelerate aging and lead to chronic diseases like heart disease, cancer, and Alzheimer's (26-28). Glucose Blocker combats inflammation with potent anti-inflammatory compounds and antioxidants. Its chromium content aids in reducing inflammation markers like C-reactive protein (CRP) and interleukin-6 (IL-6) (29).

The high flavonoid content in white mulberry leaf extract and Gymnema sylvestre helps counter harmful free radicals, mitigating inflammation. Furthermore, they inhibit the production of pro-inflammatory cytokines, reducing inflammation (30, 31).

Berberine, a powerful plant-derived compound, is celebrated for its potent anti-inflammatory and antioxidant properties. It moderates multiple pathways, including suppressing nuclear factor-kappa B (NF-ÎșB) and activating AMP-activated protein kinase (AMPK), diminishing inflammation and oxidative stress (32). Consequently, this may reduce the risk of chronic illnesses linked to oxidative stress, including cancer, cardiovascular disease, and cognitive decline (2, 20, 28).

All references

Dodge Energy Crashes

Triggered by Glucose Spikes

Sharp spikes in blood sugar levels can lead to rapid drops - known as 'energy crashes' or 'insulin crashes' - characterized by feelings of fatigue, weakness, and an inability to focus (33). Glucose Blocker helps to stabilize blood sugar levels and prevent these debilitating energy dips. This allows you to maintain a consistent level of energy throughout your day, staying active and focused without the fear of sudden fatigue.

White mulberry leaf extract and white kidney bean extract further limit the absorption of carbohydrates, thus preventing sudden increases in blood glucose (2). Berberine improves insulin sensitivity and promoting glucose metabolism, leading to more stable blood sugar levels. It does so by activating an enzyme called AMPK, an energy sensor that regulates glucose and lipid metabolism (34).

All references

Boost AMPK and FOXO3A Longevity Proteins

For Healthy Longevity

The proteins AMPK and FOXO3A are critical in regulating cell metabolism and supporting longevity. Glucose Blocker's natural ingredients are designed to activate and enhance these proteins. Chromium chloride and berberine stimulate AMPK, promoting glucose uptake and insulin sensitivity (26, 35, 36). Gymnema sylvestre activates AMPK and boosts FOXO3A activity, leading to increased gene expression associated with cellular repair and antioxidant defense, promoting cellular health and longevity (37). Furthermore, the white mulberry leaf extract can activate FOXO3A, contributing to cell repair and defense against oxidative stress (38). Thus, Glucose Blocker enhances your longevity mechanisms.

All references

Unveiling Berberine

One of Longevity's Best Kept Secrets

Berberine, a compound found in various plants like barberry and Oregon grape, is a powerful but often overlooked longevity enhancer. Used in traditional Chinese medicine, it offers a plethora of benefits from blood sugar regulation to countering cellular aging. Studies reveal berberine's potential to amplify AMPK activation, boost autophagy (the process where cells eliminate unnecessary or dysfunctional components), and curb apoptosis (cell death) induced by high glucose levels. These effects parallel those of increased physical activity and decreased caloric intake. Berberine's effectiveness is so compelling that it's often recommended to diabetic and pre-diabetic individuals alone or alongside conventional diabetes medications (28, 34). Recent studies indicate that berberine can match the effectiveness of several diabetes drugs - including metformin, a well-studied longevity-enhancing drug. Its so powerful, that daily 1 gram of berberine intake has been shown to reduce blood sugar levels by 20%, bringing them from diabetic to non-diabetic ranges (39).

All references

How to use

Healthy adults should take two (2) capsules with meals, especially meals high in carbohydrates or sugar. For enhanced effectiveness, take 15 minutes before eating. It is advisable to accompany this regimen with a balanced diet consisting of whole, unprocessed foods, and to regularly monitor glucose levels for pattern identification and necessary adjustments. For enhanced synergistic effects, combine with Longevity Foundation AM/PM.

+ behavioral protocol

Portion Control: Monitor portion sizes; overeating can cause sugar levels to spike. Choose Low Glycemic Index Foods: such as non-starchy vegetables and whole grains, which are absorbed slowly. Meal Phasing: Always start your meals with something fiber-rich, like vegetables or salad. This helps to slow glucose absorption. Take a Walk: Engaging in light movement after meals can aid in mopping up excess blood sugar.

+ WARNING

Not recommended for children, pregnant, or nursing women. Consult a healthcare provider before use, especially if you are on medication or have conditions like liver or kidney problems, heart disease, high blood pressure, cholesterol issues, or digestive disorders. Not advised for those on oral hypoglycemic agents, insulin, or other medicines affecting blood glucose levels. Not for individuals allergic or hypersensitive to any formula component.

Chromium Chloride

200 mcg

Chromium is an essential trace mineral that enhances insulin sensitivity, helping your cells effectively absorb glucose to maintain balanced blood sugar levels (20,21,36). It also supports healthy metabolism, combats oxidative stress, and promotes better lipid (fat) metabolism—key for longevity (29,36,40-43). One daily serving provides the chromium equivalent of over 100 cups of cooked broccoli (20,21), delivering powerful metabolic support in every capsule.
All references

White mulberry leaf extract

200 mg

Used for centuries in traditional Chinese medicine, white mulberry leaf extract naturally slows carb breakdown into sugars, reducing glucose absorption and preventing sharp blood sugar spikes (2,44-46). Rich in the powerful compound 1-deoxynojirimycin, it also offers antioxidant support to protect your cells from inflammation and oxidative stress (44-46). A single serving provides the equivalent of 1 kg (2.2 lbs) of ripe figs, making potent carb-control easy (2).
All references

Berberine

200 mg

Berberine, nature's powerful longevity booster, has been used for centuries in traditional medicine to help manage blood sugar and cellular aging. It activates your metabolism's master switch (AMPK), boosting fat burning, increasing insulin sensitivity, and significantly improving glucose control (26,27,35,39). Its potent antioxidant and anti-inflammatory properties fight age-related damage, enhancing cellular renewal and promoting healthier aging (28,32). Remarkably, berberine has been shown to lower blood sugar levels by as much as 20%, rivaling the effects of popular experimental anti-aging interventions like metformin (39). Berberine notably extends lifespan and health in model organisms and mice, aiding cell rejuvenation and growth, even under natural aging and chemotherapy-induced senescence.
All references

Gymnema sylvestre extract

180 mg

Gymnema sylvestre—known as the "sugar destroyer"—helps you curb sugar cravings by naturally dulling your tongue’s sugar receptors (1,9-15). This makes sweets less tempting, helping you effortlessly manage carb and sugar intake. It also supports balanced blood sugar, reducing glycation that can age your skin (1,49). Gymnema even promotes feelings of fullness, supporting easier weight management and helping you stay on track toward your longevity goals (1,9-15).
All references

White kidney bean extract

400 mg

White kidney bean extract contains phaseolamin, a powerful carb-blocker that can limit the absorption of carbohydrates from your meals (2,18-21). By inhibiting the enzyme alpha-amylase—responsible for converting carbs into sugars—it naturally reduces calorie intake and helps you manage weight(2,18-21). Simply put: fewer carbs stored means less belly fat and smoother weight-management progress.
All references

How can blood sugar spikes affect the 12 hallmarks of aging?

Learn more

Elevated blood sugar levels are linked to the development of many age-related diseases, including heart disease, dementia, and cancer.

Dr. David Sinclair, PhD. Professor in the Department of Genetics at the Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School

Founded in Oxford - we’ve done our homework

At Jung+, we're on a crusade to liberate human longevity, translating the latest scientific advancements in aging research into products and technologies that can slow aging and extend healthy lifespan

Our scientists

GMP certified

Manufactured in facilities that follow Good Manufacturing Practices (GMP), ensuring the highest quality and purity.

Scientist Approved

Formulated by experts and rigorously evaluated by scientists to ensure effectiveness and safety.

Clinical-Grade Dosage

Contains the precise dosages used in clinical studies, ensuring you receive the optimal amount for maximum benefit.

Made in the USA

Proudly produced in the USA, ensuring adherence to the highest standards of quality and safety.

Meet our JUNG+ community

“I've researched it all: Jung delivers the best”

“Feeling younger, stronger, and more vibrant every single day”

“Longevity never felt so effortless— I'm obsessed with these products!”

FAQ’s

  • Can I take Glucose Blocker if I am on a Keto diet or other low carb diets?

    Yes, Glucose Blocker can be beneficial if you're on a ketogenic or low carb diet as it helps regulate blood glucose levels and may help reduce the impact of any higher-carb meals on your blood sugar levels.

  • How long does it take to see results with the Glucose Blocker?

    The timing may vary depending on individual health status, diet, and lifestyle factors. Some may see a difference in their blood sugar levels within a few weeks, while for others it might take longer. Regular monitoring of your blood sugar levels and consistent use of the supplement is advised for best results.

  • Can Glucose Blocker help with weight loss?

    While Glucose Blocker is primarily designed to help control blood sugar levels, some ingredients, like Gymnema sylvestre and white kidney bean extract, have been associated with weight management. However, it should be used in conjunction with a balanced diet and regular exercise for optimal results.

  • How long should I take this supplement?

    This supplement can be taken long-term as part of a healthy lifestyle. Taking breaks after several months of continuous use is recommended to track changes and assess need. You may find that your relationship to carbs and sugars has radically changed over time, and you no longer feel you need support. If so, that's great! Pick another longevity goal to tackle :)

Developed by experts

Dr. Sagner is a world leading human performance specialist, sports and preventive medicine, and was the medical director at Europe’s first University medical center section for preventive medicine and lifestyle medicine. Dr Sagner is a member of the European Union Platform for Action on Diet, Physical Activity and Health and a partner of the European Innovation Partnership on Active and Healthy Aging.

Dr. Michael Sagner, MD

DIRECTOR, EUROPEAN SOCIETY OF PREVENTIVE MEDICINE
Francois-Xavier Pellay, PhD, known as the 'Longevity Molecule Hunter', is a world leading scientist and entrepreneur in the longevity industry. Pellay is a multidisciplinary scientist with a background which includes a Master's degree in Biochemistry, a Master's degree in Organic Chemistry, a Ph.D. in Bioinformatics and years of expertise in Microbiology, Molecular Biology, Cellular Biology and Biology of Aging.

Francois-Xavier Pellay, PhD

PROFESSOR | SCIENTIST | LONGEVITY MOLECULE HUNTER | FOUNDER, BIMINI BIOTECH
Dr. Fady Hannah-Shmouni, MD FRCPC, is a physician-investor at the forefront of endocrinology, genomics, and healthspan medicine. As a distinguished Professor at the University of British Columbia, he passionately empowers individuals by facilitating access to groundbreaking technologies in precision medicine, including artificial intelligence and genomic advancements.

Dr. Fady Hannah-Shmouni

LONGEVITY PHYSICIAN | PROFESSOR | YALE SCHOOL OF MEDICINE | NIH | UNIVERSITY OF BRITISH COLUMBIA
Dr. Avi Roy is an accomplished biomedical scientist, mentor, and entrepreneur with a deep-rooted passion for advancing the field of longevity. His academic journey culminated in a PhD from the University of Oxford. With over 15 years of dedicated research and development in the longevity sector, Dr. Roy has established himself as a a leading figure in this dynamic and ever-evolving field. As a mentor and investor in health-tech startups, he continues to inspire and guide the next generation of scientists and entrepreneurs.

Avi Roy

BIOMEDICAL SCIENTIST | INVENTOR | UNIVERSITY OF OXFORD | FOUNDER, UDA

Scientific studies

  • Advanced glycation end products (AGEs) and longevity

    AGEs are associated with an increased risk of cardiovascular disease and mortality in older adults. The study followed over 1,000 participants for a median of 9 years and found that those with higher levels of AGEs had a significantly higher risk of cardiovascular events and death. The authors suggest that reducing AGE intake through dietary modifications or supplements may help improve longevity and reduce the risk of chronic diseases (50).

  • Effects of chromium supplementation on glucose control

    In this study, researchers investigated the effects of chromium and polyphenols from cinnamon on insulin sensitivity in human and animal subjects. The results showed that supplementation with chromium and cinnamon improved insulin sensitivity and glucose metabolism, suggesting a potential role in managing glucose levels. The study provides evidence for using chromium to control glucose levels and insulin sensitivity (51).

  • Effects of mulberry leaf extract on the rise in blood glucose after a meal

    The study found that participants who consumed a mulberry leaf extract beverage had a significantly lower postprandial (post meal) glucose response than the control group. The researchers concluded that mulberry leaf extract might help manage postprandial glucose levels and prevent insulin resistance (52).

  • Benefits of berberine in longevity and managing diabetes

    Berberine may have a therapeutic effect on glucose metabolism and insulin resistance. The article suggests that berberine may have a protective effect on various organs in the body, which could lead to increased longevity (34).

  • Gymnema sylvestre administration decreased body weight, BMI, and very low-density lipoprotein levels in subjects with metabolic syndrome.

    This clinical study investigated the impact of Gymnema sylvestre, a medicinal plant, on metabolic syndrome, insulin secretion, and insulin sensitivity. The randomized, double-blind, placebo-controlled trial included 24 patients aged 30-60 years, diagnosed with metabolic syndrome. These patients were given G. sylvestre or a placebo twice daily before meals for 12 weeks. Post-administration, the study found significant reductions in patients' body weight, body mass index (BMI), and very low-density lipoprotein (VLDL) levels. However, there were no observed changes in metabolic syndrome components, insulin secretion, or insulin sensitivity. The results suggest that G. sylvestre can potentially aid in weight management and lipid profile improvement without affecting insulin function (53).

  • Effect of white kidney bean extract, mulberry leaf extract, and niacin-bound chromium complex on glycemic control in obese diabetic mice.

    The results showed that the food mixture with white kidney bean extract, mulberry leaf extract, and niacin-bound chromium complex improved glucose tolerance and insulin sensitivity in the mice, reduced fasting blood glucose and HbA1c levels, and improved glycemic control in obese individuals with diabetes (20).

  • Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates

    Mulberry leaf extract (MLE), containing 1-Deoxynojirimycin, has been highlighted in a study for its potential in managing blood sugar levels. The research, conducted with 15 healthy volunteers, found that MLE significantly reduces postprandial hyperglycemia by inhibiting carbohydrate digestion. The study observed lower glycemic index values for common dietary sugars such as sucrose, maltose, and maltodextrin when combined with MLE, with reductions in glycemic impact up to 53.11%. This indicates that MLE can effectively moderate blood sugar spikes following meals. The findings suggest that MLE could be beneficial in managing blood sugar responses to carbohydrate-rich foods, and it was well-tolerated by participants, underscoring its potential as a natural aid for blood sugar control (24).

  • Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevity

    This study highlights the effects of berberine in promoting longevity and enhancing cellular health. In the research, berberine's ability to activate AMP-activated kinase (AMPK) is central to its impact. This activation leads to a cascade of beneficial effects, primarily through enhancing the function of Sirt1, a protein vital for cellular survival. Sirt1 supports key processes such as autophagy, DNA repair, and mitochondrial biogenesis, crucial for maintaining cellular integrity and combating age-related damage. The study underscores berberine's potential in fostering healthful longevity by maintaining efficient cellular functions and protecting against cellular stress and aging. The findings position berberine as a noteworthy agent in targeting age-related degenerative changes and promoting overall cellular health, based on its interactions with AMPK and Sirt1 (26).

  • Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies

    Berberine has been shown to have significant health benefits, particularly in lowering cholesterol and blood sugar levels. The study reveals that berberine works by increasing cholesterol uptake in the liver and reducing the production of proteins that raise cholesterol levels. Additionally, it aids in lowering blood sugar by enhancing glucose utilization in muscle and fat cells and reducing its absorption in the intestines. In animal studies, berberine effectively reduced cholesterol levels, which is beneficial for heart health. It also showed promise in diabetic animals by lowering blood sugar levels and aiding in weight control. Clinical trials in humans have mirrored these results, with berberine demonstrating a significant reduction in cholesterol and blood sugar levels, and it did so with minimal side effects. These findings are quite promising, suggesting berberine could be a valuable natural alternative for treating certain health issues (34).

All References

  1. Kumar PM, Venkataranganna MV, Manjunath K, Viswanatha GL, Ashok G. Methanolic leaf extract of Gymnema sylvestre augments glucose uptake and ameliorates insulin resistance by upregulating glucose transporter-4, peroxisome proliferator-activated receptor-gamma, adiponectin, and leptin levels in vitro. J Intercult Ethnopharmacol. 2016;5(2):146-52.
  2. Lange E, Kęszycka PK, PaƂkowska-GoĆșdzik E, Billing-Marczak K. Comparison of Glycemic Response to Carbohydrate Meals without or with a Plant-Based Formula of Kidney Bean Extract, White Mulberry Leaf Extract, and Green Coffee Extract in Individuals with Abdominal Obesity. International Journal of Environmental Research and Public Health. 2022;19(19):12117.
  3. Lopez-Otin C, Blasco MA, Partridge L, Serrano M, Kroemer G. Hallmarks of aging: An expanding universe. Cell. 2023;186(2):243-78.
  4. Khalifa I, Xia D, Dutta K, Peng J, Jia Y, Li C. Mulberry anthocyanins exert anti-AGEs effects by selectively trapping glyoxal and structural-dependently blocking the lysyl residues of ÎČ-lactoglobulins. Bioorganic chemistry. 2020;96:103615.
  5. Vincent JB. The potential value and toxicity of chromium picolinate as a nutritional supplement, weight loss agent and muscle development agent. Sports medicine (Auckland, NZ). 2003;33(3):213-30.
  6. Kang MH, Lee MS, Choi MK, Min KS, Shibamoto T. Hypoglycemic activity of Gymnema sylvestre extracts on oxidative stress and antioxidant status in diabetic rats. J Agric Food Chem. 2012;60(10):2517-24.
  7. Barrett ML, Udani JK. A proprietary alpha-amylase inhibitor from white bean (Phaseolus vulgaris): A review of clinical studies on weight loss and glycemic control. Nutrition journal. 2011;10(1):24.
  8. Ma Y, Ratnasabapathy R, Gardiner J. Carbohydrate Craving-not everything is sweet. Current opinion in clinical nutrition and metabolic care. 2017;20(4):261.
  9. Shanmugasundaram ER, Rajeswari G, Baskaran K, Rajesh Kumar BR, Radha Shanmugasundaram K, Kizar Ahmath B. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol. 1990;30(3):281-94.
  10. Al-Romaiyan A, King AJ, Persaud SJ, Jones PM. A novel extract of Gymnema sylvestre improves glucose tolerance in vivo and stimulates insulin secretion and synthesis in vitro. Phytother Res. 2013;27(7):1006-11.
  11. Yoshikawa M, Murakami T, Matsuda H. Medicinal foodstuffs. X. Structures of new triterpene glycosides, gymnemosides-c, -d, -e, and -f, from the leaves of Gymnema sylvestre R. Br.: influence of gymnema glycosides on glucose uptake in rat small intestinal fragments. Chem Pharm Bull (Tokyo). 1997;45(12):2034-8.
  12. Yoshikawa M, Murakami T, Kadoya M, Li Y, Murakami N, Yamahara J, et al. Medicinal foodstuffs. IX. The inhibitors of glucose absorption from the leaves of Gymnema sylvestre R. BR. (Asclepiadaceae): structures of gymnemosides a and b. Chem Pharm Bull (Tokyo). 1997;45(10):1671-6.
  13. Kanetkar P, Singhal R, Kamat M. Gymnema sylvestre: A Memoir. Journal of clinical biochemistry and nutrition. 2007;41(2):77-81.
  14. Li Y, Zheng M, Zhai X, Huang Y, Khalid A, Malik A, et al. Effect of-Gymnema Sylvestre, Citrullus Colocynthis and Artemisia Absinthium on Blood Glucose and Lipid Profile in Diabetic Human. Acta Pol Pharm. 2015;72(5):981-5.
  15. Gaytan Martinez LA, Sanchez-Ruiz LA, Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of Gymnema sylvestre Administration on Glycemic Control, Insulin Secretion, and Insulin Sensitivity in Patients with Impaired Glucose Tolerance. J Med Food. 2021;24(1):28-32.
  16. Józefczuk J, Malikowska K, Glapa A, StawiƄska-WitoszyƄska B, Nowak JK, Bajerska J, et al. Mulberry leaf extract decreases digestion and absorption of starch in healthy subjects-A randomized, placebo-controlled, crossover study. Adv Med Sci. 2017;62(2):302-6.
  17. Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutrition & metabolism. 2021;18(1):41.
  18. Qin G, Wang F, Liang H, Tang S, Shekh K, Wang Y, et al. Subchronic Study of a White Kidney Bean (Phaseolus vulgaris) Extract with α-Amylase Inhibitory Activity. Biomed Res Int. 2019;2019:9272345.
  19. Nolan R, Shannon OM, Robinson N, Joel A, Houghton D, Malcomson FC. It's No Has Bean: A Review of the Effects of White Kidney Bean Extract on Body Composition and Metabolic Health. Nutrients. 2020;12(5).
  20. Tzeng HP, Chiu CY, Liu SH, Chiang MT. Improvement of Glycemic Control by a Functional Food Mixture Containing Maltodextrin, White Kidney Bean Extract, Mulberry Leaf Extract, and Niacin-Bound Chromium Complex in Obese Diabetic db/db Mice. Metabolites. 2022;12(8).
  21. Bonetti G, Herbst KL, Donato K, Dhuli K, Kiani AK, Aquilanti B, et al. Dietary supplements for obesity. Journal of preventive medicine and hygiene. 2022;63(2 Suppl 3):E160-e8.
  22. Dowis K, Banga S. The Potential Health Benefits of the Ketogenic Diet: A Narrative Review. Nutrients. 2021;13(5).
  23. Kim DW, Kang HC, Park JC, Kim HD. Benefits of the nonfasting ketogenic diet compared with the initial fasting ketogenic diet. Pediatrics. 2004;114(6):1627-30.
  24. Wang R, Li Y, Mu W, Li Z, Sun J, Wang B, et al. Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates. Medicine. 2018;97(34):e11996.
  25. Shimizu K, Iino A, Nakajima J, Tanaka K, Nakajyo S, Urakawa N, et al. Suppression of glucose absorption by some fractions extracted from Gymnema sylvestre leaves. The Journal of veterinary medical science. 1997;59(4):245-51.
  26. DiNicolantonio JJ, McCarty MF, Assanga SI, Lujan LL, O'Keefe JH. Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevity. Open Heart. 2022;9(1).
  27. McCubrey JA, Lertpiriyapong K, Steelman LS, Abrams SL, Yang LV, Murata RM, et al. Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. Aging (Albany NY). 2017;9(6):1477-536.
  28. Yin J-y, Hu R, Chen M, Tang J, Li F-y, Yang Y, et al. Effects of berberine on glucose metabolism in vitro. Metabolism: clinical and experimental. 2002;51 11:1439-43.
  29. Zhang X, Cui L, Chen B, Xiong Q, Zhan Y, Ye J, et al. Effect of chromium supplementation on hs-CRP, TNF-α and IL-6 as risk factor for cardiovascular diseases: A meta-analysis of randomized-controlled trials. Complementary therapies in clinical practice. 2021;42:101291.
  30. SĂĄnchez-Salcedo EM, Mena P, GarcĂ­a-Viguera C, MartĂ­nez JJ, HernĂĄndez F. Phytochemical evaluation of white (Morus alba L.) and black (Morus nigra L.) mulberry fruits, a starting point for the assessment of their beneficial properties. Journal of Functional Foods. 2015;12:399-408.
  31. Jangam A, Tirunavalli SK, Adimoolam BM, Kasireddy B, Patnaik SS, Erukkambattu J, et al. Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-ÎșB/MAPK pathway. Inflammopharmacology. 2023;31(2):823-44.
  32. Li Z, Geng YN, Jiang JD, Kong WJ. Antioxidant and anti-inflammatory activities of berberine in the treatment of diabetes mellitus. Evidence-based complementary and alternative medicine : eCAM. 2014;2014:289264.
  33. Hanssen NM, Kraakman MJ, Flynn MC, Nagareddy PR, Schalkwijk CG, Murphy AJ. Postprandial glucose spikes, an important contributor to cardiovascular disease in diabetes? Frontiers in cardiovascular medicine. 2020;7:570553.
  34. Pirillo A, Catapano AL. Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies. Atherosclerosis. 2015;243(2):449-61.
  35. Och A, Och M, Nowak R, PodgĂłrska D, PodgĂłrski R. Berberine, a Herbal Metabolite in the Metabolic Syndrome: The Risk Factors, Course, and Consequences of the Disease. Molecules. 2022;27(4).
  36. Anderson RA, Cheng N, Bryden NA, Polansky MM, Cheng N, Chi J, et al. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes. 1997;46(11):1786-91.
  37. Bhansali S, Shafiq N, Pandhi P, Singh AP, Singh I, Singh PK, et al. Effect of a deacyl gymnemic acid on glucose homeostasis & metabolic parameters in a rat model of metabolic syndrome. The Indian journal of medical research. 2013;137(6):1174-9.
  38. Gryn-Rynko A, Bazylak G, Olszewska-Slonina D. New potential phytotherapeutics obtained from white mulberry (Morus alba L.) leaves. Biomedicine & Pharmacotherapy. 2016;84:628-36.
  39. Xie W, Su F, Wang G, Peng Z, Xu Y, Zhang Y, et al. Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis. Frontiers in Pharmacology. 2022;13.
  40. Havel PJ. A scientific review: the role of chromium in insulin resistance. The Diabetes educator. 2004;Suppl:2-14.
  41. Janson M. Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging. Clin Interv Aging. 2006;1(3):261-5.
  42. Yin RV, Phung OJ. Effect of chromium supplementation on glycated hemoglobin and fasting plasma glucose in patients with diabetes mellitus. Nutrition journal. 2015;14:14.
  43. Sharma S, Agrawal RP, Choudhary M, Jain S, Goyal S, Agarwal V. Beneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetes. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2011;25(3):149-53.
  44. Chan EWC, Wong SK, Tangah J, Inoue T, Chan HT. Phenolic constituents and anticancer properties of Morus alba (white mulberry) leaves. Journal of integrative medicine. 2020;18(3):189-95.
  45. ƁochyƄska M. Energy and nutritional properties of the white mulberry (Morus alba L.). Journal of Agricultural Science and Technology A. 2015;5(9):709-16.
  46. Kojima Y, Kimura T, Nakagawa K, Asai A, Hasumi K, Oikawa S, et al. Effects of mulberry leaf extract rich in 1-deoxynojirimycin on blood lipid profiles in humans. Journal of clinical biochemistry and nutrition. 2010;47(2):155-61.
  47. Zheng S, Liao S, Zou Y, Qu Z, Shen W, Shi Y. Mulberry leaf polyphenols delay aging and regulate fat metabolism via the germline signaling pathway in Caenorhabditis elegans. Age (Dordr). 2014;36(6):9719.
  48. Dang Y, An Y, He J, Huang B, Zhu J, Gao M, et al. Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression. Aging Cell. 2020;19(1):e13060.
  49. Kumar V, Bhandari U, Tripathi CD, Khanna G. Anti-obesity effect of Gymnema sylvestre extract on high fat diet-induced obesity in Wistar rats. Drug research. 2013;63(12):625-32.
  50. Semba RD, Ferrucci L, Sun K, Beck J, Dalal M, Varadhan R, et al. Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women. Aging Clin Exp Res. 2009;21(2):182-90.
  51. Anderson RA. Chromium and polyphenols from cinnamon improve insulin sensitivity. Proc Nutr Soc. 2008;67(1):48-53.
  52. Kim JY, Ok HM, Kim J, Park SW, Kwon SW, Kwon O. Mulberry leaf extract improves postprandial glucose response in prediabetic subjects: a randomized, double-blind placebo-controlled trial. J Med Food. 2015;18(3):306-13.
  53. Zuñiga LY, Gonzålez-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion. Journal of medicinal food. 2017;20 8:750-4.

  • Free Shipping

    Free shipping to the continental US with all subscriptions.

    Learn more

  • 90-Day Guarantee

    Risk-free results—love it or get a full refund.

    See policy

  • Subscribe & Save

    Enjoy exclusive savings on every order. Cancel anytime.

    view terms